Host: Rabbit
Target Protein: CRBN
IR: Immunogen Range:
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 51185
Swiss Prot: Q96SW2
Source: KLH conjugated synthetic peptide derived from human CRBN:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken)
For research use only. Not intended for diagnostic or therapeutic use.