Host: Mouse

Target Protein: SARS-CoV-2 (2019-nCoV) Nucleocapsid

IR: Immunogen Range:full length

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 43740575

Swiss Prot: P0DTC9

Source: Recombinant SARS-CoV-2 Nucleocapsid Protei:full length  

Purification: affinity purified by Protein A

Storage: 1*PBS, 0.03% Proclin300. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

This antibodies specific recognition of Sars-Cov-2 (2019-ncov) nucleocapsid. Do not recognize SARS CoV nucleocapsid.