Host: Mouse

Target Protein: human CD41/ITGA2B

IR: Immunogen Range:

Clonality: Monoclonal

Isotype: Mouse IgG1, k

Entrez Gene: 3674

Swiss Prot: Q9QUM0

Source: KLH conjugated synthetic peptide derived from human CD41: 

Purification: affinity purified by Protein G

Storage: 0.01M TBS (pH7.4). Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]